Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Grid pattern of nanothick microgel network.

Guoping Chen1, Naoki Kawazoe, Yujiang Fan

  • 1Biomaterials Center, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan. guoping.chen@nims.go.jp

Langmuir : the ACS Journal of Surfaces and Colloids
|April 27, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Resolution Molecular Analyses Reveal Non-additive Impacts of Chronic Warming and Nitrogen Addition on Soil-Derived Dissolved Organic Matter.

Environmental science & technology·2026
Same author

Edge computing-based computer vision and deep transfer learning for high-throughput assessment of <i>Aspergillus flavus</i> infection in crop seeds.

Plant phenomics (Washington, D.C.)·2026
Same author

Corrigendum to 'Composite scaffolds of black phosphorus nanosheets and gelatin with controlled pore structures for photothermal cancer therapy and adipose tissue engineering' [Biomaterials 275 (2021) 120923].

Biomaterials·2026
Same author

Peptide modified lipid nanoparticles Co-Delivering IL-12 mRNA and PD-L1 siRNA for glioblastoma immunotherapy.

International journal of pharmaceutics·2026
Same author

Influence of microenvironmental viscosity on the cellular uptake of Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their anticancer effect.

Nanoscale·2026
Same author

Preterm Birth International Collaborative Australasia Branch: Expert Consensus on Diagnosis and Treatment of Neonatal Lactose Intolerance (2025).

Pediatric discovery·2026
Same journal

Controlled Secondary Growth of CAU-1-NH<sub>2</sub> Membranes with Improved CO<sub>2</sub> Separation Performance.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Facile Fabrication and Stable Mechanism of a Microscale Heavy Calcium Carbonate Suspension.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Polycationic Biocidal Coatings: The Mechanism of Their Interaction with Cells.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Atomic-Scale Displacement in Ordered SmMnO<sub>3</sub> Nanoislands.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Vacancy Defect Modulated Interfacial Thermal Transport and Phonon Localization in AlGaN/GaN Heterojunctions.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Immobilization of Ytterbium via Polyphenol Chemistry on Implant Materials for Enhanced Cytocompatibility and Antibacterial Properties.

Langmuir : the ACS journal of surfaces and colloids·2026
See all related articles

Researchers created a novel grid pattern of nanothick microgels using photolithography. This smart material exhibits reversible pH-responsive swelling and shrinking, paving the way for advanced applications.

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Nanotechnology

Background:

  • Microgels are versatile polymer networks with tunable properties.
  • Developing patterned microgel structures is crucial for advanced material applications.

Purpose of the Study:

  • To develop a novel grid pattern of two distinct nanothick microgels using photolithography.
  • To investigate the pH-responsive swelling and shrinking behavior of the patterned microgels.

Main Methods:

  • Alternate photolithography was employed to create a grid pattern of poly(acrylamide) (PAAm) and poly(acrylic acid) (PAAc) microgel stripes.
  • Scanning probe microscopy (SPM) was used to observe the microgels' structural changes in response to pH variations.

Main Results:

Related Experiment Videos

  • A perpendicular grid pattern of nanothick PAAm and PAAc microgels was successfully fabricated.
  • PAAm microgels swelled at low pH and shrank at high pH, while PAAc microgels showed the opposite behavior.
  • The overlapping PAAc-PAAm regions exhibited partially offset swelling/shrinking, demonstrating reversible, pH-induced structural changes.

Conclusions:

  • A novel, pH-responsive nanothick microgel grid pattern was successfully developed.
  • The distinct and overlapping regions show tunable responses to pH changes.
  • This technology holds potential for applications in smart actuators, sensors, drug delivery, and tissue engineering.