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Isolating cells from non-sperm cellular mixtures using the PALM microlaser micro dissection system

Belinda Anoruo1, Roland van Oorschot, John Mitchell

  • 1Victoria Police Forensic Services Department, 31 Forensic Drive, Macleod, Vic. 3085, Australia.

Forensic Science International
|April 27, 2007
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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.