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Post-discharge nutrition: what does the evidence support?
1Department of Pediatrics, University of Wisconsin, Madison, WI 53715, USA. frgreer@wisc.edu
Insights
Nutrient intake for premature infants after discharge is not standardized. Human milk may require supplementation, and close monitoring of growth and nutrient levels is essential for preterm infants.
Area of Science:
- Neonatal nutrition
- Pediatric gastroenterology
- Growth and development
Background:
- Optimal nutrition for premature infants post-discharge lacks official guidelines.
- Current evidence does not support routine use of specialized preterm formulas over term formulas.
- Human milk feeding in preterm infants raises concerns regarding adequate growth and nutrient supply.
Purpose of the Study:
- To review current understanding of nutritional needs for preterm infants after hospital discharge.
- To identify concerns and recommendations for feeding preterm infants post-discharge.
- To discuss potential long-term metabolic risks associated with early nutrition.
Main Methods:
- Literature review of existing evidence on preterm infant nutrition post-discharge.
- Analysis of nutritional requirements for achieving fetal growth trajectories.
- Discussion of metabolic programming and long-term health risks.
Main Results:
- No definitive recommendations for specialized formulas post-discharge.
- Human milk may necessitate supplementation with vitamins and iron.
- Monitoring of growth, phosphorus, and alkaline phosphatase is crucial for breastfed preterm infants.
Conclusions:
- Individualized nutritional assessment is key for preterm infants post-discharge.
- Careful monitoring is required for breastfed preterm infants to ensure adequate growth and nutrient status.
- Long-term risks like obesity and metabolic syndrome are multifactorial and may be less influenced by early nutrition compared to other factors.
Abstract:
Although there are no official recommendations for specific nutrient intakes in premature infants after hospital discharge, it is agreed that the goal should be to achieve the body composition and rate of growth of that of a normal fetus of the same postmenstrual age during the entire first year of life. A general recommendation to use the special formulas designed for preterm infants after hospital discharge in place of the formulas for term infants cannot be made from the available evidence at this time. Infants fed human milk after discharge are of the greatest concern as human milk does not in theory meet the requirements for growth in these infants. Such infants should remain on supplemental vitamins and Fe while breastfeeding, and growth as well as serum levels of phosphorus and alkaline phosphatase should be carefully monitored. The increased risk of preterm infants for obesity and the metabolic syndrome secondary to the metabolic/nutritional events early in life (programming) is likely to be small compared with the contribution of other risk factors, such as parental size, weight as an adolescent, and various lifestyle factors such as physical activity.
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