Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acid-base disorders and strong ion gap.

John A Kellum1

  • 1Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15216, USA. kellumja@upmc.edu

Contributions to Nephrology
|April 28, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Net Ultrafiltration Prescription and Practice Among Critically Ill Patients Receiving Renal Replacement Therapy: A Multinational Survey of Critical Care Practitioners.

Critical care medicine·2020
Same author

A Multinational Observational Study Exploring Adherence With the Kidney Disease: Improving Global Outcomes Recommendations for Prevention of Acute Kidney Injury After Cardiac Surgery.

Anesthesia and analgesia·2020
Same author

Community Health Care Quality Standards to Prevent Acute Kidney Injury and Its Consequences.

The American journal of medicine·2019
Same author

Lung-kidney interactions in critically ill patients: consensus report of the Acute Disease Quality Initiative (ADQI) 21 Workgroup.

Intensive care medicine·2019
Same author

Baseline tubular biomarkers in young adults with congenital heart disease as compared to healthy young adults: Detecting subclinical kidney injury.

Congenital heart disease·2019
Same author

Acute kidney injury.

Lancet (London, England)·2019

Quantitative physical chemical techniques reveal insights into metabolic acid-base disorders. The strong ion gap in critically ill patients is common and linked to higher mortality, particularly when detected early.

Area of Science:

  • Clinical chemistry
  • Critical care medicine
  • Physical chemistry

Background:

  • Metabolic acid-base disorders are significant in critical care.
  • Quantitative physical chemical techniques offer new insights.

Purpose of the Study:

  • To explore the nature and clinical significance of metabolic acid-base disorders using modern quantitative physical chemical techniques.
  • To investigate the prevalence and impact of the strong ion gap in critically ill patients.

Main Methods:

  • Application of quantitative physical chemical techniques.
  • Analysis of clinical data from critically ill patients.

Main Results:

  • Abnormalities identified by the strong ion gap are common in critically ill patients.

Related Experiment Videos

  • The strong ion gap is associated with increased mortality, especially when identified early.
  • The precise chemical nature of ions contributing to the strong ion gap remains unclear.

    • Conclusions:

    • Quantitative physical chemical methods provide valuable information on metabolic acid-base disorders.
    • The strong ion gap is a clinically significant finding in critically ill patients.
    • Further research is required to fully elucidate the strong ion gap.