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Updated: Jul 15, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Evolution of mild obstructive sleep apnea after different treatments
Johanna Sahlman1, Matti Pukkila, Juha Seppä
1Department of Otorhinolaryngology, Kuopio University Hospital and University of Kuopio, Kuopio, Finland. johanna.sahlman@fimmet.fi
Mild obstructive sleep apnea tends to worsen over time. Active treatment is recommended, as untreated patients showed significant apnea-hypopnea index increases and progression to severe sleep apnea.
Area of Science:
- Sleep Medicine
- Otolaryngology
Background:
- Mild obstructive sleep apnea (OSA) is a common condition.
- The natural prognosis and optimal treatment strategies for mild OSA require further investigation.
Purpose of the Study:
- To evaluate the long-term prognosis of mild obstructive sleep apnea.
- To compare the effectiveness of different treatment modalities for mild OSA.
Main Methods:
- A retrospective, longitudinal follow-up study.
- Fifty adult patients with mild OSA were analyzed.
- Apnea-hypopnea index (AHI) changes were assessed in untreated, operative, and continuous positive airway pressure (CPAP) groups.
Main Results:
- Untreated patients showed a significant increase in AHI, with half progressing to moderate or severe OSA.
- CPAP treatment resulted in worsening OSA in 64% of patients, but normalized AHI in 27%.
- Surgical intervention led to deterioration in only 18% of patients, with 27% achieving normalized AHI.
Conclusions:
- Mild obstructive sleep apnea has a natural tendency to progress.
- Active treatment, including surgery and CPAP, appears to be advisable for managing mild OSA.
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