Related Experiment Video
Updated: Jul 15, 2026

Evaluation of Blood Lactate and Plasma Insulin During High-intensity Exercise by Antecubital Vein Catheterization
Published on: May 18, 2018
Intravenous fluids post marathon : when and why?
1United States Naval Academy, Annapolis, Maryland 21402, USA. swpyne@annapolis.med.navy.mil
Medical professionals should establish clear guidelines for administering intravenous (IV) fluids to marathon runners. Evidence supports IV fluid use for dehydration and critical conditions, but other uses require further research.
Area of Science:
- Sports Medicine
- Emergency Medicine
- Physiology
Background:
- Marathon running presents unique medical challenges, necessitating standardized treatment protocols.
- Intravenous (IV) fluid administration is a common intervention for marathon casualties.
- Current practices for IV fluid use in marathon runners require critical evaluation regarding efficacy and safety.
Purpose of the Study:
- To scrutinize the effectiveness and safety of intravenous (IV) fluid administration in marathon runners.
- To define clear intervention selection criteria and monitoring response for commonly encountered conditions.
- To guide the development of standardized medical management protocols for marathon events.
Main Methods:
- Review of existing medical literature and clinical practices regarding IV fluid use in marathon runners.
- Analysis of evidence supporting IV fluid administration for specific conditions like dehydration, hypotension, and hypoglycemia.
- Identification of areas lacking scientific evidence, such as IV fluid use for nausea, cramping, and cooling.
Main Results:
- Established indications for IV fluids include clinical dehydration and support for unconscious, hypoglycemic, or hypotensive athletes.
- Serum sodium evaluation is recommended before initiating IV fluids.
- Limited scientific evidence supports IV fluid use for persistent nausea, generalized muscle cramping, or whole-body cooling, highlighting a need for further investigation.
Conclusions:
- Marathon medical support leaders must develop and disseminate evidence-based guidelines for IV fluid administration at aid stations.
- Standardized protocols are crucial for optimizing patient outcomes and ensuring the safe and effective use of medical interventions.
- Further research is essential to clarify the role of IV fluids in managing non-critical conditions experienced by marathon runners.
Related Concept Videos
Regulation of Water Intake
Hemodialysis III: Nursing Management
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Hemodialysis II: Procedure and Complications
Imaging Studies VII: Vascular Imaging
Continuous Renal Replacement Therapy

