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Updated: Jul 15, 2026
07:42
Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
Mental nerve neuropathy: case report and review
Amy Turner-Iannacci1, Eisa Mozaffari, Eric T Stoopler
1Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, U.S.A.
CJEM
|May 3, 2007
Summary
Mental nerve neuropathy (MNN), or numb chin syndrome, is a rare symptom often linked to cancer. Recognizing MNN is crucial for diagnosing potentially life-threatening metastatic carcinoma, especially when it mimics other jaw conditions.
Area of Science:
- Neurology
- Oncology
Background:
- Mental nerve neuropathy (MNN), also known as numb chin syndrome, is a rare neurologic symptom.
- It most commonly presents as paresthesia or numbness in the chin and lower lip, often prompting emergency department visits.
- Associated symptoms can include jaw pain and expansion.
Purpose of the Study:
- To highlight the significance of recognizing MNN as a potential indicator of metastatic carcinoma.
- To aid clinicians in the accurate diagnosis of MNN, differentiating it from other mandibular conditions.
Main Methods:
- Case report detailing MNN associated with a metastatic lesion in the mandible.
Main Results:
- The case illustrates MNN stemming from mandibular metastasis.
- This presentation underscores the importance of considering malignancy in MNN cases.
Conclusions:
- MNN can be a critical early sign of advanced cancer, specifically metastatic carcinoma.
- Prompt and accurate diagnosis of MNN is essential for timely oncologic management and can prevent misdiagnosis of other jaw pathologies.
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