Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Information loss in 2 bleb grading systems.

Anthony P Wells1, Kate James, Wayne Birchall

  • 1Wellington School of Medicine, Wellington, New Zealand. twells@eyetext.net

Journal of Glaucoma
|May 3, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dietary and mouth cancer awareness at the Royal Cornwall Hospital.

British dental journal·2026
Same author

Phase 3, Randomized, Comparison Study of Intracameral Bimatoprost Implant 10 µg and Selective Laser Trabeculoplasty.

American journal of ophthalmology·2025
Same author

Prevalence and distribution of Anaplasma phagocytophilum in ticks collected from dogs in the United Kingdom.

The Veterinary record·2021
Same author

Selective Laser Trabeculoplasty: Outcomes of Multiple Repeat Treatments.

Ophthalmology. Glaucoma·2021
Same author

New technique to reduce systemic side effects of timolol eye drops: The tissue press method-Cross-over clinical trial.

Clinical & experimental ophthalmology·2019
Same author

Selective laser trabeculoplasty versus topical medication as initial glaucoma treatment: the glaucoma initial treatment study randomised clinical trial.

The British journal of ophthalmology·2019
Same journal

Factors Associated With Retinal Nerve Fiber Layer Asymmetry in Primary Open-Angle Glaucoma Among Individuals of African Ancestry.

Journal of glaucoma·2026
Same journal

Haploinsufficiency of PITX2 in Four Chinese Families with Axenfeld-Rieger Syndrome.

Journal of glaucoma·2026
Same journal

Intraocular Pressure-Lowering Effect of Omidenepag Isopropyl as a Predictor for the Efficacy of Laser Trabeculoplasty.

Journal of glaucoma·2026
Same journal

Comparative Outcomes Between Micropulse and Slow-Coagulation Transscleral Cyclophotocoagulation in Eyes With Good Visual Acuity.

Journal of glaucoma·2026
Same journal

Machine Learning With Optical Coherence Tomography for Glaucoma Diagnosis.

Journal of glaucoma·2026
Same journal

GATT-First Surgical Sequence Reduces Complications in Combined Phacoemulsification-GATT Surgery for Glaucoma.

Journal of glaucoma·2026
See all related articles

The Moorfields Bleb Grading System (MBGS) and Indiana Bleb Appearance Grading Scale (IBAGS) effectively transfer bleb photograph data. MBGS showed higher congruity scores and may be better for clinical studies.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Surgery

Background:

  • Bleb assessment is crucial in glaucoma surgery outcomes.
  • Standardized grading systems aid in objective evaluation.
  • Existing systems require validation for data transfer accuracy.

Purpose of the Study:

  • To evaluate the effectiveness of transferring descriptive data from bleb photographs to the Moorfields Bleb Grading System (MBGS) and the Indiana Bleb Appearance Grading Scale (IBAGS).
  • To determine the accuracy and reliability of these two grading systems in representing bleb morphology and vascularity.

Main Methods:

  • 51 clinical bleb photographs were graded by two experienced observers using MBGS and IBAGS.
  • Grading scores were used to generate sketched representations of blebs.

Related Experiment Videos

  • Masked graders rated the congruity between sketches and original photographs for vascularity, morphology, and overall agreement.
  • Main Results:

    • Excellent interobserver agreement (92%-98%) was achieved for both grading systems.
    • Overall congruity scores were good-to-excellent for both IBAGS (3.2) and MBGS (4.1).
    • MBGS demonstrated higher scores for vascularity (3.9) and morphology (4.1) agreement, with less influence from photographic quality or bleb type.

    Conclusions:

    • Both MBGS and IBAGS adequately represent bleb characteristics from photographs with minimal information loss.
    • The MBGS appears to be more robust, showing higher agreement and less susceptibility to image quality and bleb variations.
    • MBGS is suggested as a potentially superior system for encoding bleb photographs for statistical analysis in clinical research.