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Updated: Jul 15, 2026

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A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
[Renal carcinoma in Silesian macroregion]
Andrzej Paradysz1, Zofia Krauze-Balwińiska, Mieczysław Fryczkowski
1Katedry i Kliniki Urologii w Zabrzu Slaskiej Akademii Medycznej w Katowicach. parady@poczta.onet.pl
Summary
Renal carcinoma (kidney cancer) occurs equally in Silesian and Opole regions, but is twice as common in men. Limited histopathological exams impact prognosis assessment for this urinary system neoplasm.
Area of Science:
- Urology
- Oncology
- Epidemiology
Context:
- Renal carcinoma is the third most frequent urinary system neoplasm.
- In Poland, approximately 3500 cases are diagnosed annually.
- This study assesses renal cell carcinoma occurrence in Poland's Silesian and Opole voivodeships.
Purpose:
- To evaluate the occurrence and characteristics of renal cell carcinoma in the Silesian and Opole voivodeships.
- To analyze patient demographics, tumor details, surgical procedures, and histopathological findings.
- To compare incidence rates between the two regions and by sex.
Summary:
- Data from 690 renal carcinoma patients (259 female, 431 male) treated in 2000 were analyzed.
- Most patients (568) were over 50 years old. Tumor size, location, and histopathological grade (G1-G3) were recorded.
- 625 patients underwent surgery, with 589 radical nephrectomies and 36 conservative operations. Lymph node metastasis was found in 64 of 388 patients.
Impact:
- Renal carcinoma incidence is similar in both voivodeships.
- Men exhibit nearly a twofold higher incidence of renal carcinoma compared to women.
- Limited histopathological examination scope affects treatment prognosis and outcome assessment.

