[Statistical analysis of 1,430 determinations of 24-hour urinary estriol clinical conclusions]

The authors used statistical methods to interpret 1,430 values of 24-hour urinary estriol. This determination is valuable in the last three months of pregnancy if values lower than 10 mg/24-hour are obtained at the 40th week, the tests must be repeated and additional examinations should be made to determine the condition of the fetus. This test is invaluable in the surveillance of cases of toxaemia of pregnancy, threatened premature births, severe forms of Rhesus incompatibility, and in cases of fetal death. This study showed that the prognosis is grave when reduced or flattened oscillations of the trace of fetal cardiac frequency are associated with very low levels of estriol.