Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An agent approach for protein function analysis in a grid infrastructure.

Alessandro Orro1, Luciano Milanesi

  • 1Institute for Biomedical Technologies - Italian National Research Council, Via Fratelli Cervi 93, I-20090 Segrate (MI) - Italy. alessandro.orro@itb.cnr.it

Studies in Health Technology and Informatics
|May 4, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feature representation for explainable CRISPR off-target prediction and base editing efficiency.

Frontiers in bioinformatics·2026
Same author

Uncovering miRNA-Disease Associations Through Graph Based Neural Network Representations.

Biomedicines·2026
Same author

Implementation of a Digital Maturity Framework for Biobanking.

Journal of biomedical informatics·2025
Same author

Deciphering the landscape of allosteric glutaminase 1 inhibitors as anticancer agents.

Bioorganic chemistry·2025
Same author

Beyond the Surface: Nutritional Interventions Integrated with Diagnostic Imaging Tools to Target and Preserve Cartilage Integrity: A Narrative Review.

Biomedicines·2025
Same author

Sudden cardiac arrest prediction via deep learning electrocardiogram analysis.

European heart journal. Digital health·2025
Same journal

The Essential Components and Critical Conditions for Success in a Learning Health System in Oncology.

Studies in health technology and informatics·2026
Same journal

Use of Artificial Intelligence in Screening for Adolescent Idiopathic Scoliosis: A Scoping Review.

Studies in health technology and informatics·2026
Same journal

Movement Related Biomechanics in Adolescent Idiopathic Scoliosis: A Review of Reviews.

Studies in health technology and informatics·2026
Same journal

The Impact of Surgical Correction of Adolescent Idiopathic Scoliosis Using Posterior Spinal Fusion on Selected Radiological Parameters and Respiratory Function.

Studies in health technology and informatics·2026
Same journal

Acute Effect of Physio-logic® Exercises on Muscle Tone and Stiffness in Adolescent Idiopathic Scoliosis Patients: A Preliminary Study.

Studies in health technology and informatics·2026
Same journal

Effects of Integrated Music and Occupational Therapy on Motor and Autonomic Function in Children with Neurogenic Scoliosis.

Studies in health technology and informatics·2026
See all related articles

Phylogenomics inference offers accurate gene product functional annotation but is computationally expensive. This study deploys this method on a distributed grid using agents to simplify user interaction and reduce costs.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Functional annotation of gene products is crucial but computationally intensive.
  • Phylogenomics inference is an accurate method for functional annotation, yet its high computational cost limits its widespread adoption.
  • Current bioinformatics workflows often require complex computational tools and manual biologist intervention.

Purpose of the Study:

  • To address the computational challenges of phylogenomics inference for gene product functional annotation.
  • To implement and deploy a phylogenomics analysis protocol in a distributed grid environment.
  • To simplify user interaction with grid computing resources for complex bioinformatics analyses.

Main Methods:

  • Development and implementation of an agent architecture for grid deployment.

Related Experiment Videos

  • Utilizing a distributed grid environment to manage computational load.
  • Streamlining the phylogenomics inference protocol for enhanced efficiency.

    • Main Results:

    • Successful deployment of the phylogenomics analysis protocol on a distributed grid.
    • Demonstration of a simplified user interaction model for grid-based bioinformatics.
    • Mitigation of computational costs associated with phylogenomics inference.

    Conclusions:

    • Agent-based architecture effectively enables the deployment of computationally demanding bioinformatics protocols on distributed grids.
    • The implemented system simplifies access to powerful analysis tools for biologists.
    • This approach enhances the feasibility of using phylogenomics inference for large-scale functional annotation.