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Updated: Jul 15, 2026

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
Published on: May 23, 2025
Wrist level and proximal-upper extremity replantation
Douglas P Hanel1, Simon H Chin
1Section of Hand and Microvascular Surgery, Department of Orthopaedics and Sports Medicine, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104-6499, USA. dhanel@u.washington.edu
Wrist-proximal replantation, though advanced, remains challenging for surgeons. These complex upper extremity surgeries require distinct techniques compared to digital replantation.
Area of Science:
- Orthopedic Surgery
- Microsurgery
- Hand Surgery
Background:
- Upper extremity replantation has evolved significantly since the 1960s.
- Techniques for digital replantation are well-established globally.
- Replantation proximal to the wrist presents unique surgical complexities.
Purpose of the Study:
- To highlight the distinct challenges of wrist-proximal replantation.
- To differentiate wrist-proximal replantation from digital replantation procedures.
- To underscore the advanced difficulties faced by hand surgeons in these specific cases.
Main Methods:
- Review of historical advancements in upper extremity replantation.
- Comparative analysis of surgical techniques for digital versus wrist-proximal replantation.
- Identification of unique anatomical and technical considerations for proximal replants.
Main Results:
- Wrist-proximal replantation remains a technically demanding procedure.
- Surgeons encounter specific difficulties not present in digital replantation.
- The complexity necessitates specialized approaches and expertise.
Conclusions:
- Despite overall advancements, wrist-proximal replantation continues to be a significant surgical challenge.
- Distinct surgical strategies are required for successful wrist-proximal limb salvage.
- Further refinement in techniques for these complex cases is warranted.
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