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Mania in a case of hyperparathyroidism
Scott W Brown1, Barin V Vyas, David R Spiegel
1Eastern Virginia Medical School, Dept. of Psychiatry and Behavioral Sciences, 825 Fairfax Ave., Norfolk, VA 23507, USA. spiegedr@evms.edu
Psychosomatics
|May 5, 2007
Summary
Primary hyperparathyroidism can cause mania, not just depression, due to high calcium levels. This suggests a broader range of psychiatric symptoms linked to hypercalcemia.
Area of Science:
- Endocrinology
- Neuropsychiatry
Background:
- Primary hyperparathyroidism is linked to psychiatric symptoms mediated by hypercalcemia.
- Existing research primarily associates hypercalcemia with depression.
Observation:
- A case report details a 52-year-old woman experiencing mania.
- She had no prior psychiatric history but presented with elevated parathyroid hormone and calcium levels.
Findings:
- Hypercalcemia, a hallmark of primary hyperparathyroidism, may induce mania.
- This challenges the traditional view of hypercalcemia solely causing depressive symptoms.
Implications:
- The spectrum of psychiatric manifestations of hypercalcemia should now include mania.
- Further research into calcium's role in diverse neuropsychiatric conditions is warranted.
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