[The current opinion on inflammatory, biochemistry and hemostatic markers and factors in atherosclerosis. Part II]

Atherosclerosis remains the leading cause of morbidity and mortality in many countries. Recent studies have established an immuno-inflammatory theory of atherosclerosis where the process of atherosclerosis has a chronic, fibroproliferative character as an immuno-inflammatory response to factors that damage vessel endothelium. The development of coronary artery disease in subjects without traditional risk factors has prompted a search for new markers of the disease, which may improve primary prevention strategies. The relationship between markers of chronic inflammation and infection and development and progression of atherosclerotic may provide a basis for establishing new methods for causative treatment of cardiovascular diseases. The markers of endothelial damage and activation of inflammatory response have a prognostic value independent of traditional risk factors.