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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
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Treatment of chronic venous insufficiency

Suman W Rathbun1, Angelia C Kirkpatrick

  • 1Department of Medicine, Cardiovascular Section, University of Oklahoma Health Sciences Center, 920 Stanton L. Young Boulevard, WP 3120, Oklahoma City, OK 73104, USA. suman-rathbun@ouhsc.edu

Current Treatment Options in Cardiovascular Medicine
|May 9, 2007
PubMed

Insights

Chronic venous insufficiency (CVI) is treated with compression therapy, which reduces venous hypertension and inflammation. While other treatments offer short-term relief, advanced endovascular and surgical options show promise for long-term improvement.

Area of Science:

  • Vascular Medicine
  • Phlebology

Background:

  • Chronic venous insufficiency (CVI) stems from venous hypertension due to valvular reflux.
  • This condition triggers pathological inflammatory processes and skin changes.

Purpose of the Study:

  • To review current treatment modalities for CVI.
  • To evaluate the efficacy of compression therapy, pharmacologic agents, herbal supplements, and endovascular/surgical interventions.

Main Methods:

  • Review of existing literature on CVI treatments.
  • Analysis of studies on compression therapy, pharmaceuticals, herbal extracts (e.g., horse chestnut), and endovascular/surgical procedures.

Main Results:

  • Compression therapy is the primary treatment, effectively reducing venous hypertension and inflammation.
  • Pharmacologic agents provide temporary symptom relief but lack long-term benefits.
  • Herbal supplements like horse chestnut seed extract show short-term efficacy but require further validation.
  • Endovascular and surgical techniques improve hemodynamics, promote ulcer healing, and enhance quality of life.

Conclusions:

  • Compression therapy remains the cornerstone for managing CVI.
  • Emerging endovascular treatments for varicose veins present promising therapeutic avenues.

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