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Updated: Jul 15, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
[The treatment of post stroke-depression and emotionalism in clinical practice]
Stine Chabert Olesen1, Brian Andersen, Allan Kofoed-Enevoldsen
1Hvidovre Hospital, Endokrinologisk Afdeling. chabert@dadlnet.dk
Introduction:
Depression and emotionalism are major consequences of stroke. The aim of this study was to assess the treatment of post stroke depression and emotionalism in clinical practice.
Materials And Methods:
Retrospective cohort study based on consecutive series of patients with acute stroke admitted to a specialized stroke unit.
Results:
180 patients were identified (f/m: 92/88; age: 73 +/- 20 years, median length of stay; 18 days). At admission 29 patients (16%) were already receiving medical treatment for depression. During hospitalization a further 24 (16%; CI 10-22%) initially untreated patients started treatment. The indication to treat was referred to in 19 cases (13: depression, 6: emotionalism). Formal psychiatric examination or rating was not applied. In one case the treatment was stopped because of side effects. The dose of medicine was adjusted in one case due to insufficient effect of treatment. None of the discharge summaries indicated the expected duration of treatment.
Conclusions:
The number of patients being treated during hospitalization was less than expected compared to the expected incidence of post stroke depression and emotionalism. The indication to treat, the duration of treatment and the incidence of side effects was not sufficiently documented. Prescription practice and evaluation of treatment effect may therefore be far from optimal.
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