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Updated: Jul 15, 2026

Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
Published on: October 3, 2025
Spontaneous uterine perforation due to pyometra presenting as acute abdomen
Loabat Geranpayeh1, Mohsen Fadaei-Araghi, Behnam Shakiba
1Department of Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:
Spontaneous perforation of the uterus is rare, its incidence being about 0.01%-0.05%. We report a rare case of diffuse peritonitis caused by spontaneously perforated pyometra. A 63-year-old woman with severe abdominal pain was admitted to our hospital. Laparotomy was performed because of the suspicion of gastrointestinal perforation with generalized peritonitis. At laparotomy, about 900 mL of pus was found in the peritoneal cavity. There were no abnormal findings in the alimentary tract, liver, or gallbladder. A total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. Pathological investigation of the surgical specimen revealed endometritis and myometritis of the uterus; but there was no evidence of malignancy, and the cervical canal was patent. Although spontaneously perforated pyometra is rare, a perforated pyometra should therefore also be considered when elderly women present with acute abdominal pain.
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