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Sleep disturbance in menopause.

Robert R Freedman1, Timothy A Roehrs

  • 1Department of Psychiatry, Wayne State University School of Medicine, and Henry Ford Hospital Sleep Disorders Center, Detroit, MI 48201, USA. aa2613@wayne.edu

Menopause (New York, N.Y.)
|May 9, 2007
PubMed
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Primary sleep disorders like sleep apnea and restless legs syndrome are common in menopausal women. Addressing hot flashes may help subjective sleep quality, but underlying disorders need attention.

Area of Science:

  • Reproductive Medicine
  • Sleep Medicine
  • Gerontology

Background:

  • Sleep disturbances are frequently reported by women during the peri- and postmenopausal transition.
  • The specific causes of these sleep complaints are not fully understood in this demographic.

Purpose of the Study:

  • To identify the underlying sources of sleep complaints in peri- and postmenopausal women experiencing disturbed sleep.

Main Methods:

  • 102 women (ages 44-56) reporting sleep disturbance were assessed using the Pittsburgh Sleep Quality Index and Hamilton Anxiety and Depression Rating Scales.
  • Polysomnography was conducted in a laboratory setting.
  • Multiple regression analysis was used to analyze the data.

Main Results:

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  • 53% of participants had sleep apnea, restless legs syndrome, or both.
  • Objective sleep quality was best predicted by apneas, periodic limb movements, and arousals.
  • Subjective sleep quality was associated with Hamilton anxiety scores and the frequency of hot flashes.

Conclusions:

  • Primary sleep disorders, including sleep apnea and restless legs syndrome, are prevalent in peri- and postmenopausal women.
  • While managing hot flashes may improve perceived sleep quality, it does not resolve underlying primary sleep disorders.
  • These primary sleep disorders require clinical attention due to potential significant morbidity and mortality.