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Quantification of right and left ventricular volumes in children with congenital heart disease by multidetector-row
Hikoro Matsui1, Satoshi Yasukochi, Keiji Haseyama
1Department of Pediatric Cardiology, Nagano Children's Hospital, 3100, Toyoshina, Toyoshina-machi, Minamiazumi-gun, Nagano, 399-8288, Japan. hikoro@jp7.so-net.ne.jp
Insights
ECG-gated multidetector-row computed tomography (MDCT) provides accurate measurements of right and left ventricular volumes in children. This non-invasive technique correlates well with cardiac catheterization, potentially reducing the need for invasive procedures.
Area of Science:
- Pediatric Cardiology
- Medical Imaging
- Cardiovascular Diagnostics
Background:
- Multidetector-row computed tomography (MDCT) is established for adult coronary artery evaluation.
- Quantitative analysis of cardiac chambers in children using MDCT is not well-established.
- Accurate assessment of ventricular volumes is crucial for pediatric cardiac care.
Purpose of the Study:
- To determine the feasibility and validation of ECG-gated MDCT for quantitative assessment of right and left ventricular volumes in children.
- To establish a non-invasive method for pediatric cardiac chamber volume measurement.
Main Methods:
- 16 pediatric patients with defined right and left ventricles were included.
- ECG-gated MDCT was used to acquire multislice cardiac images.
- End-diastolic volumes of both ventricles were calculated using direct region of interest analysis and 3D reconstruction methods.
Main Results:
- Excellent correlation was found between the two MDCT calculation methods for both ventricles (r=0.99 for LV, 0.94 for RV).
- Ventricular volume measurements by MDCT showed good correlation with cardiac catheterization results (r=0.99 for LV, 0.99 for RV).
Conclusions:
- ECG-gated MDCT is a feasible and validated tool for quantitative measurement of pediatric ventricular volumes.
- This non-invasive imaging technique correlates well with cardiac catheterization.
- MDCT may reduce the need for invasive cardiac catheterization in children.
Abstract:
Multidetector-row computed tomography (MDCT) of the heart is a new diagnostic approach for the quantitative evaluation of the coronary artery in adults. However, in children, the quantitative analysis of each cardiac chamber has not been established. We attempt to clarify the feasibility and validation of ECG-gated MDCT as a quantitative diagnostic tool to assess the right and left ventricular volume in children. The study consisted of 16 patients who had definite right and left ventricle. After obtaining multislice images by MDCT, we measured the end diastolic volume of both the right and the left ventricle by direct calculation of the region of interest and calculation from the projected image of three-dimensional reconstruction by traditional formulas. The correlation between the two calculations for both ventricles is excellent (r=0.99 for LV and 0.94 for RV, respectively). The correlations for ventricular volume between calculation of catheterization and calculation of MDCT is also good (r=0.99 for LV 0.99 for RV, respectively). Volume measurement by ECG-gated MDCT of the right and left ventricles is well correlated with that by catheterization in children and can reduce the necessity for cardiac catheterization.
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