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Published on: August 9, 2024
Madeline 2.0 PDE: a new program for local and web-based pedigree drawing.
Edward H Trager1, Ritu Khanna, Adrian Marrs
1Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan 48105, USA. ed.trager@gmail.com
Bioinformatics (Oxford, England)
|May 10, 2007
Summary
Madeline 2.0 PDE is a new pedigree drawing program designed for genetic studies. It efficiently handles complex family trees, ensuring clear and aesthetically pleasing visualizations for genetic research.
Area of Science:
- Genetics
- Bioinformatics
Background:
- The Madeline 2.0 Pedigree Drawing Engine (PDE) is a software tool developed for genetic research.
- It is designed to address the challenges of visualizing large and intricate pedigrees.
Purpose of the Study:
- To introduce the Madeline 2.0 PDE, a program for generating pedigree drawings.
- To enhance the readability and aesthetics of complex pedigree structures in genetic studies.
Main Methods:
- Utilizes a hybrid algorithm to draw consanguineous loops as cyclic graphs where possible, resorting to acyclic graphs to prevent line crossings.
- Employs a similar hybrid approach to manage matings between distant descendants from different founding groups, minimizing line crossings.
- Developed in object-oriented C++ and released under the GNU General Public License (GPL).
Main Results:
- The Madeline 2.0 PDE can process large and complex pedigrees, producing clear and aesthetically pleasing drawings.
- The program generates pedigree drawings automatically from command-line input files.
- Output is available in Scalable Vector Graphics (SVG) format, compatible with web browsers and vector graphics editors.
Conclusions:
- Madeline 2.0 PDE offers an effective solution for visualizing complex pedigrees in genetic studies.
- The software's hybrid algorithm and SVG output enhance the usability and accessibility of pedigree data.
- An experimental public web service is available for accessing the tool's functionality.
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