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Gingival hyperplasia induced by nifedipine
1Second Department of Oral Surgery, Nihon University school of Dentistry, Matsudo, Japan.
The Journal of Nihon University School of Dentistry
|September 1, 1991
Abstract:
We describe 4 cases of gingival hyperplasia induced by nifedipine, together with clinical and histological findings. Hyperplasia of the interdental papillae was observed in all cases. Histologic examination showed multilayered epithelial parakeratosis with variations in the width, proliferation, reticulation and elongation of the rete pegs. Substitution of another drug and improvement of oral hygiene led to reduction of the gingival overgrowth without gingivectomy. These treatments are essential for gingival hyperplasia induced by nifedipine.