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Updated: Jul 15, 2026

High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
Published on: June 21, 2011
Statistical image reconstruction for inconsistent CT projection data
1Institute of Medical Engineering, Universität Lübeck, Lübeck, Germany. buzug@imt.uni-luebeck.de
Objectives:
The filtered backprojection is not able to cope with metal-induced inconsistencies in the Radon space which leads to artifacts in reconstructed CT images. A new algorithm is presented that reduces the drawbacks of existing artifact reduction strategies.
Methods:
Inconsistent projection data are bridged by directed interpolation. These projections are reconstructed using a weighted maximum likelihood algorithm (lambda-MLEM). The correlation coefficient between images of a torso phantom marked with steel markers reconstructed with lambda-MLEM and images of the same torso slice without markers quantifies the quality achieved. For clinical data, entropy maximization is presented to obtain appropriate weightings.
Results:
Different interpolation strategies have been applied. The quality of reconstruction sensitively depends on the complexity of interpolation. A directional interpolation gives best results. However, the quality of the images can be further improved by an appropriate weighing within lambda-MLEM. This has been demonstrated with data from a torso phantom, a jaw with amalgam fillings and a hip prosthesis.
Conclusions:
lambda-MLEM image reconstruction using data from directional Radon space interpolation is a new approach for metal artifact reduction. The weighting in this statistical approach is used to reduce the influence of residual inconsistencies in a way that optimal artifact suppression is obtained by optimizing a compromise between residual inconsistencies and void data. The image quality is superior compared with other artifact reduction strategies.
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