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A new HLA-A*30 variant, A*3018, identified by sequence-based typing in the Chinese population

H-Y Zou1, Z Li, C-P Shao

  • 1Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China. shallylizhen@yahoo.com.cn

Tissue Antigens
|May 12, 2007
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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...