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Distinction between pore assembly by staphylococcal alpha-toxin versus leukotoxins

Olivier Joubert1, Joëlle Voegelin, Valérie Guillet

  • 1Laboratoire de Physiopathologie et d'Antibiologie des Infections Bactériennes Emergentes et Nosocomiales, EA 3432, Institut de Bactériologie de la Faculté de Médecine, Université Louis Pasteur-Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.

Journal of Biomedicine & Biotechnology
|May 15, 2007
PubMed
Summary

Staphylococcal bipartite leukotoxins and alpha-toxin are pore-forming toxins. Modifications to leukotoxin N-termini do not impair function, indicating structural differences in pore formation.

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