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Updated: Jul 15, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Pyoderma gangrenosum and Churg-Strauss syndrome]
A Dejardin Botelho1, F Delesalle, E Delaporte
1Service de pneumologie et immunoallergologie, cliniques des maladies respiratoires, hôpital Calmette, CHRU de Lille, 59037 Lille cedex, France.
Introduction:
Pyoderma gangrenosum (PG) is an unusual dermatitis witch is associated at least in half of the cases with a systemic illness.
Case Record:
A 54 year-old woman suffering from Churg and Strauss syndrome has been monitored for many years. She was hospitalized in dermatology unit for a PG without showing any activity signs of her angeitis. After a well conducted localized treatment, the cutaneous lesions rapidly improved.
Discussion:
PG physiopathology is still not well known, but its interest lies in the fact of the high number of associated internal pathologies and is probably linked to granulomatosis such as Churg and Strauss angeitis.
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