[Physico-chemical properties of alveolar surfactant in intermediate type allergy]

Development of sensitization involved accumulation of protein, lipoproteins and neutral triglycerides in lung surfactant, which inactivated surface active phospholipids and decreased the surface activity of surfactant. In anaphylactic shock a decrease in content of phospholipids and alteration of their fatty acid spectrum occurred as a result of which the moistening capacity of the covering complex was lowered and expiration of the bronchoalveolar secretion was restricted thus contributing to formation of asphyxia.