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Protocols for Testing the Toxicity of Novel Insecticidal Chemistries to Mosquitoes
Published on: February 13, 2019
[Evaluating two pyrethroids in dengue vector control in Putumayo, Colombia]
Mirley Castro1, Nilson Quintana, Martha L Quiñones P
1Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Revista De Salud Publica (Bogota, Colombia)
|May 16, 2007
Summary
Two pyrethroid insecticides effectively reduced Aedes aegypti mosquito density by over 80% in Puerto Leguizamo, offering a new dengue control strategy. However, sustained reduction was not observed due to emerging adults from untreated areas.
Area of Science:
- Medical Entomology
- Public Health
- Vector Control
Background:
- Dengue fever is a significant public health concern transmitted by Aedes aegypti mosquitoes.
- Effective vector control strategies are crucial for preventing dengue outbreaks.
Purpose of the Study:
- To evaluate the efficacy of two pyrethroid insecticides against Aedes aegypti.
- To provide data for informed decision-making in dengue control programs.
Main Methods:
- Ultra-low volume (ULV) application of highcis-Permethrin and ss-cypermethrin in a smoke-generating formulation.
- Field evaluation in 16 blocks in Puerto Leguizamo, Colombia, from July to December 2004.
- Mosquito mortality assessed using sentinel cages; density and larval presence monitored weekly.
Main Results:
- Both insecticides achieved an immediate 80% reduction in mosquito density post-treatment.
- A shift in mosquito location from indoors to outdoors was observed after application.
- Sustained mosquito density reduction over five weeks was not achieved, likely due to adult emergence from untreated deposits.
Conclusions:
- The evaluated pyrethroid insecticides demonstrate high efficacy (>80%) in reducing Aedes aegypti populations.
- These insecticides present a viable alternative for integrated dengue control strategies.

