Extracellular ascorbate modulates glutamate dynamics: role of behavioral activation

Michael I Sandstrom1, George V Rebec

  • 1Central Michigan University, Psychology Department, Mount Pleasant, MI, USA. sands1m@cmich.edu <sands1m@cmich.edu>

BMC Neuroscience
|May 18, 2007
PubMed
Summary

Elevated ascorbate (AA) increases striatal glutamate (GLU) release, but this effect is modulated by behavioral arousal. The study found that environmental light conditions significantly influenced the relationship between AA levels and GLU efflux in rats.

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