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Published on: October 4, 2017
Injectable matrices and scaffolds for drug delivery in tissue engineering
James D Kretlow1, Leda Klouda, Antonios G Mikos
1Department of Bioengineering, Rice University, Houston, TX 77251-1892, USA.
Advanced Drug Delivery Reviews
|May 18, 2007
Summary
Injectable materials offer minimally invasive options for both drug delivery and tissue engineering. This review explores adapting drug delivery injectables into scaffolds for tissue regeneration.
Area of Science:
- Biomaterials Science
- Drug Delivery Systems
- Tissue Engineering
Background:
- Injectable matrices and depots are crucial in drug delivery research.
- Tissue engineering classically uses scaffolds, cells, and bioactive molecules for tissue growth.
- Injectable materials offer minimal invasiveness, benefiting both fields.
Purpose of the Study:
- To review injectable materials and processing techniques in tissue engineering and drug delivery.
- To explore adapting drug delivery injectables for tissue engineering scaffolds.
Main Methods:
- Literature review of injectable materials and processing techniques.
- Analysis of cross-disciplinary applications in drug delivery and tissue engineering.
Main Results:
- Significant overlap exists between injectable materials used in drug delivery and tissue engineering.
- Drug delivery injectables show potential for adaptation as tissue engineering scaffolds.
Conclusions:
- Injectable materials represent a promising area for synergistic advancements in drug delivery and tissue engineering.
- Further research can bridge the gap between these fields, enhancing regenerative medicine strategies.
