Related Experiment Video
Updated: Jul 14, 2026

Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research
Published on: August 31, 2013
Lyme neuroborreliosis: infection, immunity, and inflammation
Andrew R Pachner1, Israel Steiner
1Department of Neurosciences, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA. pachner@umdnj.edu
Abstract:
Lyme neuroborreliosis (LNB), the neurological manifestation of systemic infection with the complex spirochaete Borrelia burgdorferi, can pose a challenge for practising neurologists. This Review is a summary of clinical presentation, diagnosis, and therapy, as well as of recent advances in our understanding of LNB. Many new insights have been gained through work in experimental models of the disease. An appreciation of the genetic heterogeneity of the causative pathogen has helped clinicians in their understanding of the diverse presentations of LNB.
Related Concept Videos
Encephalitis ll: Pathophysiology
Encephalitis l: Introduction
Arboviral Encephalitis
Bacterial Meningitis II: Pathophysiology
Inflammation: Introduction
Inflammatory Bowel Disease III: Crohn's Disease

