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Updated: Jul 14, 2026
07:42
An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
Fungal infections in solid organ transplantation
Fernanda P Silveira1, Shahid Husain
1Division of Infectious Diseases, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Medical Mycology
|May 19, 2007
Summary
Fungal infections pose a significant risk to solid organ transplant recipients, with rising resistance and emerging fungal types. This review covers updated epidemiology, diagnosis, and treatment strategies for these vulnerable patients.
Area of Science:
- Medical Mycology
- Transplantation Medicine
- Infectious Diseases
Background:
- Fungal infections are a major cause of illness and death in solid organ transplant (SOT) recipients.
- Candida and Aspergillus species are the most common culprits of invasive fungal infections.
- Infection rates and types vary significantly by transplant type, with liver recipients prone to Candida and lung recipients to Aspergillus.
Purpose of the Study:
- To review recent epidemiological shifts in fungal infections among SOT recipients.
- To highlight updated information on diagnosing, preventing, and treating these infections.
- To address the emergence of antifungal resistance and non-Aspergillus molds.
Main Methods:
- Literature review of recent epidemiological studies.
- Synthesis of current data on diagnosis and management.
- Focus on changes in fungal infection patterns in SOT patients.
Main Results:
- Solid organ transplant recipients face ongoing risks from fungal infections.
- Emerging resistant strains of Candida and other molds (non-Aspergillus) are increasingly reported.
- Specific transplant types show distinct patterns of fungal infection incidence.
Conclusions:
- Updated knowledge of fungal infection epidemiology is crucial for SOT care.
- Current diagnostic, prophylactic, and therapeutic strategies require ongoing evaluation.
- Addressing antifungal resistance and emerging pathogens is essential for improving outcomes.
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