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Related Experiment Videos

A new pulsatile total artificial heart using a single centrifugal pump.

K Imachi1, T Chinzei, Y Abe

  • 1Institute of Medical Electronics, Faculty of Medicine, University of Tokyo, Japan.

ASAIO Transactions
|July 1, 1991
PubMed
Summary

A novel pulsatile total artificial heart (TAH) uses a single pump and valves for dual circulation. This system demonstrates feasibility for a miniaturized, implantable artificial heart with controlled flow balance.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Artificial Organs

Background:

  • Total artificial heart (TAH) systems are crucial for end-stage heart failure.
  • Existing TAH designs often involve complex pumping mechanisms.
  • A simplified, pulsatile TAH is needed for improved patient outcomes and miniaturization.

Purpose of the Study:

  • To develop and evaluate a novel pulsatile total artificial heart (TAH) system.
  • To assess the feasibility of using a single centrifugal pump (CFP) for biventricular support.
  • To determine the potential for miniaturization and total implantation.

Main Methods:

  • A new TAH system was designed using a single centrifugal pump (CFP) and two three-way solenoid valves.
  • The CFP and valves were configured to alternately perfuse pulmonary and systemic circulation.

Related Experiment Videos

  • A prototype was tested in a mock circulatory system.

    • Main Results:

    • A pulsatile TAH was successfully produced using a single CFP.
    • The system achieved a pulsatile output of 5 L/min with a normal flow waveform.
    • Flow balance between the right and left sides was easily controlled by adjusting valve switching duration.

    Conclusions:

    • A single CFP and valve system can generate pulsatile flow for a TAH.
    • The developed TAH prototype demonstrates controllable flow balance and waveform.
    • The system's design is amenable to miniaturization, indicating feasibility for a totally implantable TAH.