Related Experiment Video
Updated: Jul 14, 2026

06:08
Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
Published on: May 26, 2019
New accelerator facility for carbon-ion cancer-therapy
Koji Noda1, Takuji Furukawa, Takashi Fujisawa
1Department of Accelerator and Medical Physics, National Institute of Radiological Sciences.
Journal of Radiation Research
|May 22, 2007
Summary
Carbon-ion therapy, utilizing the Heavy Ion Medical Accelerator of Chiba (HIMAC), has successfully treated over 3,000 patients since 1994. New facilities are being developed to expand access to this advanced cancer treatment.
Area of Science:
- Medical Physics
- Oncology
- Accelerator Technology
Background:
- Carbon-ion therapy has demonstrated significant clinical advancements since its inception in 1994.
- The Heavy Ion Medical Accelerator of Chiba (HIMAC) has treated over 3,000 patients, leading to its recognition as advanced medical technology in Japan.
- High-reliability operations and technological advancements in beam delivery and accelerators have underpinned the success of carbon-ion therapy.
Purpose of the Study:
- To summarize the development and future plans for carbon-ion therapy facilities.
- To detail the design and R&D of a new accelerator facility for widespread carbon-ion cancer therapy in Japan.
- To outline the ongoing design of a new treatment facility at HIMAC for further therapeutic development.
Main Methods:
- Leveraging ten years of operational experience with the HIMAC facility.
- Developing key technologies for accelerator and beam-delivery systems, focusing on facility downsizing for cost reduction.
- Initiating design and R&D studies for a new accelerator facility and a new HIMAC treatment facility.
Main Results:
- Construction of a new carbon-ion therapy facility began at Gunma University in April 2006.
- Ongoing development of accelerator and beam-delivery technologies for a proposed new facility.
- Design work has commenced for a new treatment facility at HIMAC.
Conclusions:
- Carbon-ion therapy, particularly using HIMAC, has a proven track record and is recognized as advanced medical technology.
- New facilities are under development to enhance the accessibility and cost-effectiveness of carbon-ion cancer therapy.
- Future developments at HIMAC aim to further advance carbon-ion therapy techniques.
Related Concept Videos
Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Radiation: Applications
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
The average...
Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

