Related Experiment Video
Updated: Jul 14, 2026
03:43
Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
Published on: September 13, 2022
Contemporary use of cervical cerclage
Vincenzo Berghella1, Jolene Seibel-Seamon
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA 19107, USA. vincenzo.berghella@jefferson.edu
Clinical Obstetrics and Gynecology
|May 22, 2007
Summary
Cervical cerclage, a procedure to prevent preterm birth, shows effectiveness in high-risk pregnancies. Randomized trials confirm its benefit for women with recurrent pregnancy loss or short cervix.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
Background:
- Cervical cerclage is a surgical procedure to prevent preterm birth.
- Historically, its efficacy was not rigorously evaluated by controlled trials.
- It was initially designed for pregnancies with prior preterm birth and current cervical changes.
Purpose of the Study:
- To evaluate the efficacy of cervical cerclage in preventing pregnancy loss and preterm birth.
- To identify specific indications and optimal timing for cerclage placement.
Main Methods:
- Review of controlled randomized trials on cervical cerclage efficacy.
- Analysis of outcomes based on patient history (prior preterm birth, pregnancy loss) and ultrasound findings (cervical length).
Main Results:
- Transvaginal cerclage likely prevents second-trimester loss or preterm birth in women with a history of three or more such events.
- History-indicated cerclage is most effective when placed between 12-14 weeks.
- Ultrasound-indicated cerclage (cervical length <25 mm) in women with prior preterm birth is effective when placed between 14 and 23 6/7 weeks.
Conclusions:
- Cervical cerclage is a valuable intervention for specific high-risk pregnancies.
- Timing and indication (history vs. ultrasound) are crucial for cerclage success in preventing preterm birth.
