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Erectile dysfunction in men with angiographically documented coronary artery disease
Seyed Kazem Foroutan1, Mohammadreza Rajabi
1Department of Urology, Mostafa Khomeini Hospital, Shahed University, Tehran, Iran. skf356@yahoo.com
Insights
Erectile dysfunction (ED) is common in men with coronary artery disease (CAD) and correlates with the extent of arterial blockage. ED can also precede CAD diagnosis by approximately two years.
Area of Science:
- Cardiology
- Urology
- Vascular Health
Background:
- Coronary artery disease (CAD) affects a significant number of men.
- Erectile dysfunction (ED) is a common condition that can impact quality of life.
Purpose of the Study:
- To evaluate erectile function in men with CAD.
- To determine the relationship between the severity of ED and the extent of coronary artery stenosis.
Main Methods:
- Assessed erectile function using the Sexual Health Inventory for Men (SHIM) in 401 non-diabetic men with CAD.
- Coronary artery stenosis was documented via cardiac angiography.
Main Results:
- 46.4% of men had ED (SHIM score ≤ 21).
- ED was more prevalent and SHIM scores were lower in men with multi-vessel CAD.
- ED symptoms preceded CAD diagnosis in 41.9% of patients, with an average interval of 23 months.
Conclusions:
- ED is highly prevalent in men with CAD.
- The severity of ED correlates with the extent of CAD.
- ED may serve as an early indicator of underlying CAD, appearing up to two years prior to diagnosis.
Introduction:
We evaluated erectile function of men with coronary artery disease (CAD) and the relation between the degree of erectile dysfunction (ED) and the extent of coronary artery stenosis on cardiac angiography.
Materials And Methods:
Nondiabetic men with CAD documented by angiography were evaluated for ED. Erectile function was assessed by a 5-item version of the International Index of Erectile Dysfunction, the Sexual Health Inventory for Men (SHIM).
Results:
Of 401 men, 186 (46.4%) had ED (SHIM score, 21 or less). Men with ED were more likely to have more than 1 stenotic cardiac vessel (P<.001). The mean SHIM score was 20.9 +/- 7.6, 12.9 +/- 9.2, and 14.3 +/- 9.1 for men with 1-, 2-, and 3-vessel disease, respectively (P<.001). Multivariate analysis showed that only the SHIM score had a relationship with the number of involved vessels (P<.001); the SHIM score was lower and ED was more frequent in men with more than 1 vessel involvement. Forty-one patients (19.1%) without ED and 45 (24.2%) with ED had a positive history of myocardial infarction (P=.21). Symptoms of ED had appeared prior to CAD detection in 78 out of 189 patients (41.9%) with a mean time interval of about 23 months (range, 10 to 36 months).
Conclusion:
Our finding showed that the prevalence of ED is relatively high in patients with CAD, and has a relationship with the extent of CAD. Furthermore, ED may occur before CAD with an average interval of 2 years.
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