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RADAR: a web server for RNA data analysis and research.

Mugdha Khaladkar1, Vivian Bellofatto, Jason T L Wang

  • 1Bioinformatics Program and Department of Computer Science, New Jersey Institute of Technology, NJ 07102, USA.

Nucleic Acids Research
|May 23, 2007
PubMed
Summary
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RADAR is a web server for RNA data analysis, offering sequence and structure alignment. It aids in understanding RNA functionality, motif detection, and molecule clustering.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Molecular Biology

Background:

  • RNA molecules play crucial roles in various biological processes.
  • Analyzing RNA sequences and structures is essential for understanding their function.
  • Existing tools may not fully integrate sequence and structural information for RNA analysis.

Purpose of the Study:

  • To introduce RADAR, a web server for comprehensive RNA data analysis.
  • To provide tools for aligning structure-annotated RNA sequences.
  • To facilitate RNA research through advanced analysis functionalities.

Main Methods:

  • Development of a web server integrating sequence and structure information for RNA analysis.
  • Implementation of pairwise and multiple structure alignment algorithms.

Related Experiment Videos

  • Inclusion of database search, clustering, and consensus structure prediction capabilities.

    • Main Results:

    • RADAR enables alignment of RNA sequences considering both sequence and structure.
    • The server supports constrained alignment of RNA secondary structures.
    • RADAR predicts consensus structures for sets of RNA sequences.

    Conclusions:

    • RADAR offers a versatile platform for RNA data analysis and research.
    • The tool assists in understanding RNA functionality and detecting structural motifs.
    • RADAR supports RNA molecule clustering and other important RNA mining operations.