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[A new saponin from Koelreuteria paniculata]

Hai-min Lei1, Qiang Li, Wei Bi

  • 1College of Traditional Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China. leihaimin@yahoo.com.cn

Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|May 24, 2007
PubMed
Abstract

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Esters to Carboxylic Acids: Saponification01:25

Esters to Carboxylic Acids: Saponification

Esters can be hydrolyzed to carboxylic acids under acidic or basic conditions. Base-promoted hydrolysis of esters is a nucleophilic acyl substitution reaction in which esters react with an aqueous base, followed by an acid to give carboxylic acids. This reaction is also known as saponification because it forms the basis for making soaps from fats.
The reaction requires a base in stoichiometric amounts, which participates in the reaction and is not regenerated later. So, the base acts as a...