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Published on: December 20, 2024
Inflammatory pseudotumor of the spleen: CT and MRI findings
Pei-Chun Ma1, Shu-Chiang Hsieh, Jerry Chin-wei Chien
1School of Medicine, Taipei Medical University, Taipei, Taiwan, Republic of China.
Abstract:
Inflammatory pseudotumors rarely occur in the spleen. We report such a case with characteristic computed tomography (CT) and magnetic resonance imaging (MRI) findings. A CT scan showed an isodense nodular mass with gradual mild enhancement on delayed-phase contrast-enhanced images. MRI showed a mass with isointense signal on T1-weighted images and hypointense signal on T2-weighted images. The tumor mass showed progressive inhomogeneous enhancement on gadolinium-enhanced images. The patient received splenectomy, and histologic diagnosis was compatible with inflammatory pseudotumor.
Insights
Inflammatory pseudotumors are rare splenic masses. This case highlights characteristic imaging findings on computed tomography (CT) and magnetic resonance imaging (MRI) that aid in diagnosis before surgical removal.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Inflammatory pseudotumors (IPTs) are uncommon benign lesions.
- Splenic IPTs are exceptionally rare, posing diagnostic challenges.
Observation:
- A patient presented with a splenic mass.
- Computed tomography (CT) revealed an isodense nodular lesion with delayed enhancement.
- Magnetic resonance imaging (MRI) demonstrated T1 isointensity, T2 hypointensity, and progressive inhomogeneous enhancement.
Findings:
- Imaging characteristics were suggestive of IPT.
- Histopathological examination post-splenectomy confirmed the diagnosis of inflammatory pseudotumor.
Implications:
- Characteristic CT and MRI findings can help differentiate splenic IPTs from other splenic neoplasms.
- Early recognition of imaging patterns may guide clinical management and avoid unnecessary aggressive treatments.