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How to treat hypertension in patients with peripheral artery disease

Denis L Clement1, Marc L Debuyzere

  • 1Department of the Dean, Ghent University Hospital, Building 3K3, 185, De Pintelaan, B-9000 Ghent, Belgium. denis.clement@UGent.be

Current Hypertension Reports
|May 24, 2007
PubMed

Insights

Physicians often underestimate peripheral artery disease (PAD) risk, which hypertension exacerbates. Managing PAD and hypertension requires a focus on triple therapy and controlling total cardiovascular risk for better patient outcomes.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Pharmacology

Background:

  • Peripheral artery disease (PAD) risk is frequently underestimated by physicians.
  • Hypertension significantly increases the risk of peripheral artery disease.
  • Early detection of PAD and hypertension is crucial for preventing cardiovascular events.

Purpose of the Study:

  • To review the management of peripheral artery disease as a cardiovascular risk factor.
  • To emphasize the importance of triple therapy in managing PAD.
  • To discuss antihypertensive drug classes and their peripheral circulatory effects.

Main Methods:

  • Literature review on PAD management and hypertension treatment.
  • Analysis of the role of antiplatelet drugs, ACE inhibitors, and statins in triple therapy.
  • Evaluation of antihypertensive medications concerning their impact on peripheral circulation.

Main Results:

  • Triple therapy (antiplatelet drugs, angiotensin-converting enzyme inhibitors, statins) is highlighted for PAD management.
  • Individual antihypertensive drugs show minimal differences in peripheral circulatory effects.
  • Controlling total cardiovascular risk is paramount in patients with PAD and hypertension.

Conclusions:

  • Effective management of PAD necessitates addressing associated risk factors like hypertension.
  • A comprehensive approach to cardiovascular risk reduction is more critical than selecting specific antihypertensive agents.
  • Physicians must improve PAD risk assessment and management strategies.

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