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Premature twins of a mother with Graves' disease with discordant thyroid function: a case report
M J O'Connor1, A O Paget-Brown, W L Clarke
1Division of General Pediatrics, Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908-0386, USA.
Insights
Maternal Graves
Area of Science:
- Endocrinology
- Neonatal Medicine
- Obstetrics
Background:
- Graves' disease in pregnant mothers can affect newborns.
- Thyroid dysfunction is a known complication in infants born to mothers with Graves' disease.
Observation:
- This study observed twin infants born to a mother diagnosed with Graves' disease during pregnancy.
- The infants presented with simultaneous hyperthyroidism and hypothyroidism.
Findings:
- The twin infants exhibited concurrent hyperthyroidism and hypothyroidism.
- This case highlights a rare presentation of neonatal thyroid dysfunction.
Implications:
- Understanding concurrent thyroid dysfunction in twins is crucial for neonatal care.
- Early diagnosis and management are vital for affected infants.
- This case may inform clinical guidelines for managing neonatal thyroid disorders in high-risk pregnancies.
Abstract:
Thyroid dysfunction is recognized in the newborns of mothers affected by Graves' disease during pregnancy. We describe the development of concurrent hyperthyroidism and hypothyroidism in the twin infants of a mother with Graves' disease diagnosed during pregnancy.
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