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Renal cell carcinoma: late recurrence in 2 cases
European Urology
|January 1, 1991
Summary
Late recurrences of renal cell carcinoma (RCC) can occur over a decade after nephrectomy. This study highlights rare solitary metastases in unusual locations, emphasizing the need for long-term patient surveillance.
Area of Science:
- Oncology
- Urology
- Surgical Pathology
Background:
- Renal cell carcinoma (RCC) is a significant malignancy.
- Nephrectomy is a primary treatment modality for RCC.
- Late recurrence of RCC necessitates extended follow-up protocols.
Observation:
- Two patients experienced late recurrences of RCC 16 and 11 years post-nephrectomy.
- Metastases were solitary in both cases.
- Uncommon metastatic sites included the vastus externus muscle and colon.
Findings:
- The reviewed literature of 5,758 RCC patients identified only two colon metastases and one temporal muscle metastasis.
- None of the previously reported metastases were solitary.
- This case series presents the first documented solitary metastases in these rare locations.
Implications:
- These findings suggest that solitary, late-onset metastases in unusual sites can occur in RCC patients.
- Extended surveillance may be warranted for RCC survivors.
- Further research into the mechanisms of late and solitary RCC metastasis is needed.