Cadaveric kidney transplantation: five years experience at a single center

Area of Science:

• Nephrology
• Transplantation Surgery
• Public Health

Background:

• Historically, living donors predominated renal transplantation in Iran.
• A recent increase in cadaveric organ donation is observed.
• This study reviews a 5-year experience with kidney transplantation from cadaveric donors.

Purpose of the Study:

• To evaluate the outcomes of kidney transplantation using cadaveric donors.
• To assess graft survival and renal function in recipients.
• To determine the viability of cadaveric organ donation in Iran.

Main Methods:

• 122 kidneys from 61 brain-dead donors were transplanted into 114 end-stage renal disease patients between 1998 and 2004.
• Donors were victims of road traffic accidents.
• Recipients were followed for at least 1 year to assess graft survival and renal function.

Main Results:

• The 1-year graft survival rate was 92.3%.
• Mean serum creatinine at 1 year was 1.76 +/- 0.79.
• Other organs, including heart, liver, and lung, were also transplanted with varying outcomes.

Conclusions:

• Cadaveric donors represent a significant and viable source for organ donation in Iran.
• The findings support the expansion of cadaveric organ donation programs in developing countries.
• Successful kidney transplantation from cadaveric donors can be achieved with careful management and follow-up.