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Carbonated beverages and chronic kidney disease
Tina M Saldana1, Olga Basso, Rebecca Darden
1Epidemiology Branch, National Institute of Environmental Health Sciences (NIEHS), NIH, DHHS, Research Triangle Park, NC 27709, USA.
Epidemiology (Cambridge, Mass.)
|May 26, 2007
Summary
Drinking two or more colas daily significantly increases the risk of developing chronic kidney disease (CKD). This association was observed for both regular and artificially sweetened cola beverages, highlighting a potential dietary risk factor for kidney health.
Area of Science:
- Nephrology
- Epidemiology
- Nutritional Science
Background:
- Carbonated beverage intake is associated with chronic kidney disease (CKD) risk factors like diabetes, hypertension, and kidney stones.
- Cola beverages, containing phosphoric acid, may alter urine composition, potentially promoting kidney stone formation.
Purpose of the Study:
- To investigate the association between carbonated beverage consumption, specifically colas, and the risk of developing chronic kidney disease.
- To determine if different types of cola beverages (regular vs. artificially sweetened) have varying impacts on CKD risk.
Main Methods:
- A case-control study was conducted using data from 465 newly diagnosed CKD patients and 467 community controls in North Carolina.
- Data collection occurred between 1980 and 1982, examining the relationship between carbonated beverage intake and CKD.
Main Results:
- Consuming two or more colas per day was linked to a 2.3-fold increased risk of CKD (95% CI: 1.4-3.7).
- This elevated risk was consistent for both regular (OR=2.1) and artificially sweetened colas (OR=2.1).
- Noncola carbonated beverages did not show a significant association with CKD risk (OR=0.94).
Conclusions:
- Preliminary findings suggest a potential link between cola consumption and an increased risk of chronic kidney disease.
- Further research is warranted to confirm these findings and elucidate the underlying mechanisms.
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