Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Brain Abscess l: Introduction

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

Bacterial Signaling

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...

Bacterial Meningitis I: Introduction

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Accelerating patient access to oncology medicines with multiple indications in Europe.

Journal of market access & health policy·2021

Same author

A case of PAPASH syndrome in a young man carrying a novel heterozygote missense variant in PSTPIP1.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021

Same author

Nosocomial influenza in south-western Swiss hospitals during two seasonal epidemics: an observational study.

The Journal of hospital infection·2021

Same author

Creation and Validation of a Condition-Specific Venous Thromboembolism Risk Assessment Tool for Open Ventral Hernia Repair Patients.

Journal of vascular surgery. Venous and lymphatic disorders·2016

Same author

[Urinary incontinence in older women: what can a GP do?].

Revue medicale suisse·2016

Same author

CSF lactate for accurate diagnosis of community-acquired bacterial meningitis.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2015

Search research articles

Related Experiment Video

Updated: Jul 14, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

[Infection of a total knee prosthesis with Brucella spp].

F Marbach¹, L Saiah, J F Fischer

¹Service d'orthopédie et de traumatologie de l'appareil moteur, Hôpital du Chablais, 1870 Monthey. francesco.marbach@fhv.ch

Revue Medicale Suisse

|May 29, 2007

Summary

Brucellosis can cause osteoarticular infections, including rare prosthetic joint infections. This case highlights successful treatment using prosthesis exchange and long-term antibiotics for Brucella prosthetic joint infection.

More Related Videos

A Periprosthetic Joint Candida albicans Infection Model in Mouse

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

Related Experiment Videos

Last Updated: Jul 14, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

A Periprosthetic Joint Candida albicans Infection Model in Mouse

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

Area of Science:

Infectious Diseases
Orthopedic Surgery
Microbiology

Background:

Brucellosis is a global zoonotic disease with osteoarticular complications being most common.
Prosthetic joint infections (PJIs) are significant complications of total joint arthroplasty, often caused by staphylococci.
Brucella spp. are infrequently reported as causative agents of PJIs.

Observation:

A rare case of prosthetic joint infection caused by Brucella spp. was identified.
Polymerase chain reaction (PCR) was utilized for definitive diagnosis of Brucella infection.
The patient presented with symptoms indicative of a prosthetic joint infection.

Findings:

The patient with Brucella prosthetic joint infection was successfully treated.
Treatment involved a two-stage exchange of the infected prosthesis.
Long-term antimicrobial therapy was crucial for eradicating the Brucella infection.

Implications:

This case underscores the importance of considering Brucella spp. in prosthetic joint infections, even when rare.
Effective management requires a combination of surgical intervention and prolonged antibiotic treatment.
Early and accurate diagnosis using molecular methods like PCR is vital for successful outcomes in prosthetic joint infections.