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Related Experiment Video

Updated: Jul 14, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
09:22

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Congenital pulmonary airway malformation: CT-pathologic correlation.

Masashi Shimohira1, Masaki Hara, Masanori Kitase

  • 1Department of Radiology, Nagoya City University School of Medicine, Nagoya, Japan. m_shimohira@yahoo.co.jp

Journal of Thoracic Imaging
|May 29, 2007
PubMed
Summary

Computed tomography (CT) effectively identifies congenital pulmonary airway malformation (CPAM) type 1 when the largest cyst exceeds 2.5 cm. However, differentiating CPAM subtypes using CT can be challenging with small cysts or solid lesions.

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Last Updated: Jul 14, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
09:22

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Area of Science:

  • Pulmonology
  • Radiology
  • Pediatric Surgery

Background:

  • Congenital pulmonary airway malformation (CPAM) is a spectrum of congenital lung malformations.
  • CPAM is histologically classified into five subtypes (0-4) by Stocker.
  • Accurate preoperative diagnosis of CPAM subtype is crucial for appropriate management.

Purpose of the Study:

  • To correlate computed tomography (CT) findings with the pathological subtypes of CPAM.
  • To evaluate the predictability of CPAM subtypes based on CT imaging characteristics.

Main Methods:

  • Retrospective review of 13 pathologically proven CPAM cases.
  • CT findings were categorized into three groups based on cyst size and morphology (Group A: largest cyst >2.5 cm, Group B: largest cyst ≤2.5 cm, Group C: solid lesions).
  • Correlation between CT-based groups and Stocker's pathological classification was assessed.

Main Results:

  • Eight cases were classified as Group A (largest cyst >2.5 cm), all corresponding to Stocker's type 1.
  • Three cases in Group B (largest cyst ≤2.5 cm) included one type 2 and two mixed types (1 and 4).
  • Two cases in Group C (solid lesions) included one type 3 and one type 2.

Conclusions:

  • CT findings of a largest cyst >2.5 cm strongly predict CPAM type 1.
  • Distinguishing between CPAM types 1, 2, and 4 is difficult when small cystic components are present.
  • Differentiating between CPAM types 2 and 3 can be challenging when lesions appear solid on CT.