Pulpal responses after application of current adhesive systems to deep cavities

Area of Science:

• Dental Materials Science
• Biomaterials
• Restorative Dentistry

Background:

• Adhesive systems are crucial in modern restorative dentistry.
• Understanding pulpal tissue reactions to these materials is essential for clinical success.
• Varying compositions of adhesive systems may elicit different biological responses.

Purpose of the Study:

• To comparatively evaluate pulpal tissue reactions to four different adhesive systems.
• To assess the histopathological effects of Etch and Prime (EP), Single Bond (SB), Clearfil SE Bond (CSE), and Prompt L-Pop (PLP) on dog teeth dentin.
• To correlate remaining dentin thickness (RDT) with pulpal responses to adhesive materials.

Main Methods:

• Class V cavities were prepared in healthy dog teeth with a mean RDT of 0.55-0.68 mm.
• Four adhesive systems (EP, SB, CSE, PLP) were applied to the prepared cavities.
• Pulpal tissue responses were histopathologically assessed at 7, 21, and 65 days postoperatively.

Main Results:

• Etch and Prime (EP) and Prompt L-Pop (PLP) showed significantly greater adverse inflammatory responses.
• Single Bond (SB) and Clearfil SE Bond (CSE) exhibited significantly less disorganization in the odontoblastic zone at 65 days.
• A thicker predentin zone was observed with Single Bond (SB) application.

Conclusions:

• Adhesive system choice impacts pulpal tissue response.
• Single Bond (SB) and Clearfil SE Bond (CSE) appear to be more biocompatible with pulpal tissue compared to EP and PLP.
• Slight to moderate inflammation and odontoblast reduction are associated with these adhesive systems depending on the material and RDT.