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Updated: Jul 14, 2026

3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis
06:46

3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis

Published on: February 25, 2022

NOX in liver fibrosis.

Samuele De Minicis1, David A Brenner

  • 1Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, NY 10026, USA.

Archives of Biochemistry and Biophysics
|May 29, 2007
PubMed
Summary

NADPH oxidase, crucial for host defense and cell signaling, drives liver fibrosis by activating hepatic stellate cells (HSCs). Inhibiting this enzyme complex in HSCs offers a potential therapeutic target for liver fibrosis.

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