Related Experiment Video
Updated: Jul 14, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
Absence of endometrium as a cause of primary amenorrhea
Bulent Berker1, Salih Taşkin, Elif Aylin Taşkin
1Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine, Ankara, Turkey.
Objective:
To describe congenital endometrial absence.
Design:
Case report.
Setting:
University hospital.
Patient(S):
A 32-year-old woman presented with primary amenorrhea and infertility. Hormone analysis, physical and gynecologic examinations, transvaginal ultrasonography, and karyotype analysis were normal.
Intervention(S):
Progesterone challenge test, laparoscopy, hysteroscopy were performed, and hysteroscopic biopsies were obtained from the uterine cavity.
Main Outcome Measure(S):
Presence of endometrium, menstruation.
Result(S):
The progesterone challenge test was negative. Laparoscopy revealed normal pelvic structures. Evaluation of biopsies from uterine cavity revealed absence of endometrium.
Conclusion(S):
Endometrial absence is a differential diagnosis for primary amenorrhea; assessment of the uterine cavity and obtaining biopsy samples may help in diagnosis of suspected cases before they undergo assisted reproduction and can avoid unnecessary treatment.
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