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Hyperplastic persistent pupillary membranes with congenital corneal anomalies
Deepa Viswanathan1, Prema Padmanabhan, Aditi Johri
1Medical and Vision Research Foundation, Tamil Nadu, India.
Journal of Cataract and Refractive Surgery
|May 29, 2007
Summary
This case study details a 14-year-old girl with congenital vision impairment due to persistent pupillary membranes. Surgical removal significantly improved her vision in both eyes.
Area of Science:
- Ophthalmology
- Genetics
Background:
- Congenital vision impairment can stem from various ocular anomalies.
- Persistent pupillary membranes (PPM) are remnants of fetal iridopupillary connections, potentially causing visual disturbances.
Observation:
- A 14-year-old female presented with lifelong impaired vision in her left eye.
- Ocular examination revealed bilateral extensive persistent pupillary membranes, microcornea, cornea plana, and posterior keratoconus.
- Initial uncorrected visual acuity was 0.2 (logMAR) in the right eye and 1.9 (logMAR) in the left eye.
Findings:
- Surgical excision of the bilateral persistent pupillary membranes was performed using vitreous microscissors.
- Post-operative visual acuity improved to 0.1 (logMAR) in the right eye and 1.3 (logMAR) in the left eye at 6 months.
- No significant intraoperative or postoperative complications were observed.
Implications:
- Surgical intervention for persistent pupillary membranes can effectively restore visual function in cases of congenital vision impairment.
- This case highlights the importance of early diagnosis and surgical management for complex ocular malformations.
- Further research into the genetic and developmental factors underlying these combined ocular anomalies is warranted.
