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Mechanical and dose delivery accuracy evaluation in radiosurgery using polymer gels.

Panagiotis Sandilos¹, Elias Tatsis, Lampros Vlachos

¹Department of Radiology, Medical School, University of Athens, Areteion Hospital, Athens, Greece.

Journal of Applied Clinical Medical Physics

|May 30, 2007

Summary

Polymer gel dosimetry accurately verified mechanical and dose delivery in Leksell gamma knife radiosurgery for multiple brain targets. This Magnetic Resonance Imaging (MRI) technique ensures precision for complex stereotactic radiosurgery treatments.

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Published on: March 11, 2021

Area of Science:

Medical Physics
Radiotherapy
Medical Imaging

Background:

Stereotactic radiosurgery (SRS) requires precise mechanical accuracy and dose delivery.
Evaluating SRS accuracy, especially for multiple targets, is crucial for effective treatment.
Polymer gel dosimetry offers a method for 3D dose verification.

Purpose of the Study:

To assess the mechanical and dose delivery accuracy of Leksell gamma knife SRS.
To evaluate the efficacy of polymer gel dosimetry for verifying SRS treatments with multiple targets.
To validate the use of Magnetic Resonance Imaging (MRI) for polymer gel dosimetry in SRS.

Main Methods:

Two polymer gel dosimeter formulations were prepared and irradiated using a custom phantom.
Treatment plans for four brain metastases were created using Leksell gamma knife.
Irradiated gels were analyzed using a 1.5 T Philips ACS NT MR imager to determine mechanical and dose accuracy.

Main Results:

Polymer gel dosimetry successfully determined mechanical accuracy by comparing planned and measured shot coordinates.
Dose delivery accuracy was confirmed by comparing measured maximum doses and dose distributions with treatment planning calculations.
The technique proved capable of verifying the entire SRS treatment chain for multiple targets.

Conclusions:

Polymer gel dosimetry is a viable method for verifying mechanical and dose delivery accuracy in Leksell gamma knife SRS.
This technique is effective for complex treatments involving multiple targets.
MRI-based polymer gel dosimetry enhances quality assurance in stereotactic radiosurgery.